Economic Modelling & Statistical Analyses
Access specialized expertise in health economic modelling and advanced statistical analyses through our dedicated team of experts. Capabilities span de novo model development, model repair and refinement, local adaptations, indirect treatment comparisons, and network meta-analyses. Every project is centred around your asset, indication, and strategic objectives.
Our team is passionate about strengthening the economic value story of each asset, identifying opportunities to maximize its value proposition, and delivering targeted analyses that keeps evidence current, compelling, and relevant to decision-makers.
Economic evaluations supported across different geographies
HEOR projects delivered by partners
What we deliver
Cost-effectiveness analyses
Cost-effectiveness and cost-utility models spanning partitioned survival, Markov, microsimulation, discrete-event simulation, and efficiency frontier approaches. Tailored best to your asset and aligned with reference cases and decision-making needs.
Budget impact modelling
Development and adaptation of payer-ready models designed around your asset, target population, and landscape. We focus on flexible inputs and scenarios to enable local adaptation and support payer negotiations.
Network meta-analyses
Frequentist and Bayesian NMAs supported by rigorous feasibility assessments and heterogeneity, consistency, and uncertainty evaluations. We prioritize robust estimates to inform economic models and reinforce value.
Population-adjusted indirect comparisons
MAICs and STCs to address evidence gaps when head-to-head trials are unavailable. We deliberate to find the most appropriate method to account for different populations, and generate relevant comparative efficacy estimates to support your access strategy.
Model adaptation and refinement
Adapt, validate, and optimize existing models to meet evolving requirements and market-specific payer expectations. We provide localization, debugging, restructuring, and methodological refinements to improve accuracy, transparency, flexibility, and relevance.
Targeted updates
Keep analyses current with targeted updates incorporating new clinical data, pricing, comparators, and further scenarios. We work efficiently to refine existing analyses and address evolving evidence requirements, payer feedback, and market access priorities.
How we work
- 01
Scoping and strategic alignment
Defining the decision problem, identifying relevant comparators, and aligning analytical approaches with methodological requirements and expectations of decision-makers.
- 02
Model development and adaptation
Craft de novo model or adapt existing tailored to asset and reimbursement needs, with transparent methods, assumptions, and validation to withstand payers and HTA agency scrutiny.
- 03
Model validation
Ensure model accuracy and reliability through rigorous blinded quality checks, sensitivity analyses, and scenario testing to assess uncertainty and demonstrate the robustness of results.
- 04
Finalization and ongoing support
Comprehensive technical documentation and practical user guides, dedicated collaboration to address reviewer questions, refine analyses, and support optimal reimbursement decisions.
Every model passes four review layers before it reaches the client.
Self QC
Blinded QC
Senior QC
Optimization
Why Frontier HEOR
Purposeful and flexible scope
We work collaboratively to define whether it is a new build, repair or single update, prioritizing what you need, and maximizing value. We want you to avoid unnecessary work or expenditure.
Expertise across therapeutic areas
We have extensive experience in statistical and economic analyses across diverse therapeutic areas, bringing these insights and tailored methodologies to your asset.
Built for scrutiny
We produce analyses that go beyond ticking boxes, instead focusing on incorporating strategic insights, as well as methodological rigor and transparency to mitigate risk and support optimal outcomes.